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Treating Patients with Wake-Up Stroke: The Experience of the AbESTT-II Trial
Stroke 39:3277-3282, Adams,H.P.,et al, 2008
See this aricle in Pubmed

Article Abstract
Although the baseline characteristics of the wake-up group of subjects were similar to those of persons enrolled in the nonwake-up group, their outcomes were much poorer. Patients with wake-up stroke may not tolerate reperfusion therapies even when started within a short time of awakening.
 
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